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Completed Clinical Trials

Molecular Predictors of Pemetrexed and Carboplatin Response in Malignant Pleural Mesothelioma (MPM) Patients

By April 24, 2017No Comments

Condition

MALIGNANT PLEURAL MESOTHELIOMA

Estimated Enrollment: 121

Age Group: 18 Years and older   (Adult, Senior)

Gender: All

Study Type: Observational

Study Design Allocation: Observational Model: Cohort|Time Perspective: Retrospective

Study ID Numbers: ONC/OSS-04/2008

Study First Received: March 23, 2009

Last Updated: December 1, 2014

Estimated Primary Completion Date: December 2011

 

Primary Outcome Measures:

Evaluate the expression and allelic variants of a panel of candidate genes involved in the resistance to drugs, the genome wide copy number changes in patients treated with drugs combination in the first line|Evaluate retrospectively the correlation between gene expression and polymorphisms in candidate genes and array-CGH data, immunohistochemistry data, and clinical data.

Sponsors and Collaborators:

Istituto Clinico Humanitas

Website Link: https://ClinicalTrials.gov/show/NCT00867711

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