Condition
Advanced Malignant Mesothelioma|Localized Malignant Mesothelioma|Malignant Ascites|Primary Peritoneal Cavity Cancer|Recurrent Malignant Mesothelioma
Estimated Enrollment: 80
Age Group: 18 Years and older (Adult, Senior)
Gender: All
Study Type: Interventional
Study Design Allocation: Intervention Model: Single Group Assignment|Masking: Open Label|Primary Purpose: Diagnostic
Study ID Numbers: NCI-2012-02438|UPCC# 05901|P01CA087971|CDR0000069134
Study First Received: January 4, 2002
Last Updated: January 15, 2013
Estimated Primary Completion Date: September 2007
Primary Outcome Measures:
Level of hypoxia in tumor nodules|Inter- and intra-patient variability of hypoxia by EF5 binding|Levels of microvascular density by PECAM/CD31 staining|Relationships among levels of hypoxia, microvascular density, and photosensitizer levels|Associations between hypoxia and photosensitizer levels in tumor nodules with clinical outcome periodically until disease recurrence|Toxicity of EF5 administration
Sponsors and Collaborators:
National Cancer Institute (NCI)
Website Link: https://ClinicalTrials.gov/show/NCT00028782
